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Medchemexpress LLC Clindamycin-¹³C,d₃ | 2140264-63-5 | 99.9% | 1 MG
Supplier: Medchemexpress LLC HYB1455S11MG
Clindamycin-13C,d3 is a 13C- and deuterium labeled version of Clindamycin, a broad-spectrum, orally active bacteriostatic lincosamide antibiotic. It inhibits bacterial protein synthesis and can suppress the expression of virulence factors in *Staphylococcus aureus* at sub-inhibitory concentrations. Resistance to Clindamycin occurs due to enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). It reduces the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), or alpha-haemolysin (Hla). Additionally, Clindamycin can be used in malaria research.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes (hydrogen, carbon, and other elements) are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
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