Thermo Scientific Chemicals Clindamycin hydrochloride, 97%

Description

Clindamycin hydrochloride, CAS # 21462-39-5, is a lincosamide antibiotic. | CAS: 21462-39-5 | C18H34Cl2N2O5S | 461.439 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Clindamycin is a lincosamide antibiotic derived from lincomycin that has antibiotic activity against aerobic gram-positive cocci, and parasitic protozoa
• Clindamycin reversibly binds to the 50s bacterial ribosomal subunit, thus inhibiting protein synthesis

Applications

• Clindamycin has been used to enhance bacterial colonization in research mice during the study of commensal gut microbiota
• Clindamycin has been used to study biofilm-mediated antibiotic resistance in an in vitro model of G. vaginalis
• Clindamycin was used as a selection agent to isolate, enumerate, and identify Lactobacillus spp. from probiotic dairy products

Specifications

Chemical Identifiers

• CAS: 21462-39-5
• Molecular Formula: C18H34Cl2N2O5S
• Molecular Weight (g/mol): 461.439
• InChI Key: AUODDLQVRAJAJM-PIPVPTKYSA-N
• PubChem CID: 134129519
• IUPAC Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
• SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl

• Type: Clindamycin Hydrochloride
• Melting Point: 156.0°C to 159.0°C
• Infrared Spectrum: Authentic
• Water: 6% max.
• Quantity: 10 mg
• Solubility Information: Solubility in water: ca 50g/L. Other solubilities: soluble in pyridine, ethanol, dmf
• Formula Weight: 461.45
• Percent Purity: 97%
• Chemical Name or Material: Clindamycin hydrochloride

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

SDS

RUO – Research Use Only