Clindamycin hydrochloride monohydrate

Description

Clindamycin hydrochloride, CAS # 21462-39-5, is the salt of clindamycin, a derivative of the broad-spectrum bacteriostatic antibiotic lincomycin. | CAS: 58207-19-5 | C18H34Cl2N2O5S | 461.439 g/mol

Clindamycin hydrochloride monohydrate is an antibacterial agent that is a semisynthetic analog of lincomycin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Clindamycin is a lincosamide antibiotic that disrupts protein synthesis by interfering with the aminoacyl-tRNA ribosome complex

• Clindamycin decreases sebaceous gland activity and blocks the neuromuscular junction

Application

• Clindamycin is commonly used in laboratory applications to inhibit the growth anaerobic microbes, but has some effectiveness against aerobic microbes as well

• It can be used in the laboratory study of cell culture for resistance testing, or in antibiotic allergic reaction studies

Specifications

Chemical Identifiers

• CAS: 58207-19-5
• Molecular Formula: C18H34Cl2N2O5S
• Molecular Weight (g/mol): 461.439
• MDL Number: MFCD07793327
• InChI Key: AUODDLQVRAJAJM-NFOLQJLNSA-N
• PubChem CID: 131632848
• IUPAC Name: (2S,4R)-N-[2-chloro-1-[(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
• SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl

• Type: Clindamycin Hydrochloride Monohydrate
• Physical Form: Powder
• Color: White
• Quantity: 1 g
• Beilstein: 4070786
• Merck Index: 14,2356
• Solubility Information: Soluble in water
• Formula Weight: 479.46 (461.44 Anhydrous)
• Chemical Name or Material: Clindamycin hydrochloride monohydrate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	244-398-6
RTECSNumber	GF2275000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only