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Eurofins Discoverx CLK1, active, 250 µg. (14-920M)
Supplier: Eurofins Discoverx 14920M
N-terminal 6xHis-tagged recombinant, human CLK1 amino acids 130-end. CLK1 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. For detailed product information, visit www.discoverx.com/proteins.
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