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Apexbio Technology LLC Clodronate Disodium 22560-50-5 50mg
Supplier: Apexbio Technology LLC B170950
Clodronate Disodium is a synthetic bisphosphonate designed to inhibit osteoclast-mediated bone resorption thereby interfering with bone remodeling processes Clodronate Disodium exerts its biological activity primarily by inducing apoptosis of osteoclasts and hindering their formation and function Liposome-encapsulated Clodronate Disodium formulations are also used experimentally to selectively deplete macrophages in vivo Based on these pharmacological properties Clodronate Disodium holds research potential in studies of osteoclast biology bone metabolic pathways osteoporosis metastatic bone disease arthritis and in investigating macrophage-mediated inflammatory and autoimmune responses as well as tumor-associated macrophage functions
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