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Medchemexpress LLC Clodronic acid disodium salt | 22560-50-5 | 100.5% | 100 MG
Supplier: Medchemexpress LLC HYB0657A100MG
Clodronic acid disodium salt is a first-generation bisphosphonate that acts as an orally active osteoclastic bone resorption inhibitor. It is used in conditions characterized by high bone turnover, such as Paget's disease and osteolytic bone metastases.
- Induces rapid apoptosis in osteoclasts
- Prevents ADP translocation into mitochondria
- Inhibits ATP production, leading to apoptosis
- Demonstrated to slightly decrease hindpaw swelling in in vivo studies
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