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Medchemexpress LLC Clodronic acid disodium salt | 22560-50-5 | 100.50% | 250 MG
Supplier: Medchemexpress LLC 250MGHYB0657A
Clodronic acid disodium salt is a first-generation bisphosphonate that acts as an orally active osteoclastic bone resorption inhibitor. It can be utilized in cases of high bone turnover, Paget's disease, and osteolytic bone metastases. It induces rapid apoptosis in osteoclasts by preventing ADP translocation into mitochondria after internalization via resorption, which inhibits ATP production and leads to the release of cytochrome C into the cytoplasm.
- First-generation bisphosphonate
- Orally active osteoclastic bone resorption inhibitor
- Induces apoptosis in osteoclasts
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