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Apexbio Technology LLC Clofibrate 637-07-0 5g
Supplier: Apexbio Technology LLC B36105000
Clofibrate (CAS 637-07-0) is a small-molecule agonist targeting peroxisome proliferator-activated receptor alpha (PPAR-alpha) It is designed to activate PPAR-alpha thereby regulating lipid and lipoprotein metabolism pathways Clofibrate exerts its biological activity primarily through PPAR-alpha activation leading to enhanced peroxisome proliferation and fatty acid oxidation In both human and mouse models Clofibrate demonstrates agonist activity with EC50 values of 55 M and 500 M respectively Based on these pharmacological properties Clofibrate holds research potential in investigating lipid metabolism triglyceride regulation and the roles of PPAR-alpha signaling in hyperlipidemia and related metabolic disorders
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