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Apexbio Technology LLC Clomipramine HCl 17321-77-6 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC B22345.1

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Clomipramine hydrochloride (CAS 17321-77-6) is a tricyclic compound that inhibits monoamine transporters acting as a potent blocker of the serotonin transporter (SERT Ki 0 14 nM) with additional inhibitory activity at the dopamine (DAT Ki 3 nM) and norepinephrine (NET Ki 54 nM) transporters By impeding the reuptake of these neurotransmitters clomipramine HCl modulates synaptic concentrations and neurotransmission This compound is utilized in neuropharmacological research to investigate monoaminergic signaling transporter pharmacology and the molecular mechanisms underlying psychiatric and neurological disorders

Catalog No. 50-000-90775


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