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Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | >99.5% | 50 MG
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Supplier:  Medchemexpress LLC HYB0457R50MG

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Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. It is a tricyclic antidepressant suitable for the research of depression and obsessive compulsive disorder (OCD).

  • Clomipramine hydrochloride can inhibit reuptake of both noradrenaline and 5-HT, with a stronger inhibition on 5-HT reuptake.
  • It interferes with autophagic flux and severely compromises the viability of tumorigenic cells upon cytotoxic stress.
  • Clomipramine hydrochloride reduces immobility in the forced swimming test, which is a behavioral model for antidepressants.
  • It also inhibits the OCD animal model, marble burying behavior in mice.

Catalog No. 50-004-05920


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