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Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | MFCD00069234 | 99.6% | 25 MG
Supplier: Medchemexpress LLC 25MGHYB0457R
Clomipramine hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. It acts as a tricyclic antidepressant, primarily researched for its effects on depression and obsessive compulsive disorder (OCD). It significantly inhibits both noradrenaline and 5-HT reuptake, with a stronger selectivity for 5-HT.
- Potent 5-HT reuptake blocker with an IC50 value of 1.5 nM
- Used in research for depression and obsessive compulsive disorder (OCD)
- Inhibits noradrenaline and 5-HT reuptake, stronger for 5-HT
- Interferes with autophagic flux, impacting tumorigenic cell viability
- Reduces autophagy in neuronal primary cultures
- Can induce hyperglycemia in mice
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