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Cayman Chemical ClorgylInhydrochlorIde 100mg
SDP

Supplier:  Cayman Chemical 15925100 MG

Encompass_Preferred

A dual p38a and p38B MAPK inhibitor (Kis 0.0079 and 0.025 UM respectively in cell-free assays) selective for p38a and p38B MAPK over p38Y and p38 MAPK at 10 UM inhibits LPS-induced TNF-a production in isolated rat and human PBMCs (IC50s 0.6 and 0.13 UM respectively) decreases disease severity in a mouse model of collagen-induced arthritis at 0.8-20 mg/kg improves survival normalizes blood pressure and reduces increases in plasma levels of HDL LDL and triglycerides in spontaneously hypertensive stroke-prone rats fed a high-salt high-fat diet

Catalog No. 50-296-9332


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