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Medchemexpress LLC Closantel (sodium) | 61438-64-0 | 99.8% | 685.06 | 200 MG
Supplier: Medchemexpress LLC HY17596A200MG
Closantel sodium is a halogenated salicylanilide with potent anti-parasitic activity. It acts as a potent and highly specific *Onchocerca volvulus* chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. This compound inhibits the *O. volvulus* L3 to L4 molt of developing organisms. It is highly specific for filarial family chitinases compared to those from protozoans and the human chitinase, human chitotriosidase.
- Potent anti-parasitic activity.
- Highly specific inhibitor of filarial family chitinases.
- Less effect on protozoans and human chitinase.
- For research use only.
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