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Medchemexpress LLC Clozapine | 5786-21-0 | 99.8% | C18H19ClN4 | 50 MG
Supplier: Medchemexpress LLC HY1453950MG
Clozapine (HF 1854) is an antipsychotic agent used for the research of schizophrenia. It has high affinity for several neuroreceptors. Clozapine acts as a potent antagonist of dopamine D2 (Ki of 75 nM), inhibits the muscarinic M1 receptor (Ki of 9.5 nM) and serotonin 5HT2A receptor (Ki of 4 nM), and is a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM).
- Antipsychotic used in schizophrenia research
- High affinity for various neuroreceptors
- Potent antagonist of dopamine D2
- Inhibits muscarinic M1 receptor and serotonin 5HT2A receptor
- Potent and selective agonist at the muscarinic M4 receptor
- Available in solid and solution forms
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