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Cayman Chemical Clozapine N-oxide, 34233-69-7, 10 mg
SDP

Supplier:  Cayman Chemical 1688210

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Molecular Formula C18H19ClN4O, Purity ≥98%, Formula Weight 342.8, Synonyms: 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, CNO; A metabolite of clozapine and muscarinic DREADD agonist (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively); prevents action potential firing in cultured hippocampal neurons transiently expressing hM4D receptors; increases glutamate in the nucleus accumbens core and inhibits cue-induced reinstatement of cocaine-seeking behavior in rats transfected with hM3Dq DREADD receptors.

Catalog No. NC1310113


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