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Medchemexpress LLC Clozapine N-oxide | 34233-69-7 | 99.9% | 342.82 | 1 ML

Supplier: Medchemexpress LLC HY1736610MM/1ML
Clozapine N-oxide is a major metabolite of Clozapine and acts as an agonist for human muscarinic designer receptors (DREADDs). It activates the DREADD receptors hM3Dq and hM4Di but cannot cross the blood-brain barrier. Clozapine, its parent compound, is a potent dopamine antagonist and a selective muscarinic M4 receptor (EC50=11 nM) agonist.
- Purity: 99.87%
- Molecular weight: 342.82
- Formula: C18H19ClN4O
- Appearance: Solid, light yellow to yellow color
- Solubility in DMSO: 100 mg/mL (291.70 mM)
- Solubility in H2O: < 0.1 mg/mL (insoluble)
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 1 year, -20°C for 6 months
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