Learn More
Apexbio Technology LLC Clozapine N-oxide (CNO) 34233-69-7 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A33175.1

Clozapine N-oxide (CNO CAS 34233-69-7) is a metabolic derivative of the atypical antipsychotic drug clozapine primarily known for its applications as a chemogenetic actuator Biologically inert in typical mammalian systems CNO selectively activates engineered muscarinic receptors such as the M3-designer receptors exclusively activated by designer drugs (DREADDs) Additionally CNO influences receptor expression levels exposure in cortical neuron cultures reduces 5-HT2 receptor density significantly Due to its specificity CNO is extensively utilized in neuroscience research to modulate neuronal activity non-invasively through chemogenetic approaches
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.