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Medchemexpress LLC Clozapine N-oxide (dihydrochloride) | 2250025-93-3 | 99.7% | 415.74 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY17366A100MG

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Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and acts as an agonist for human muscarinic designer receptors (DREADDs). It activates the DREADD receptors hM3Dq and hM4Di. This compound cannot cross the blood-brain barrier. Clozapine, its parent compound, is a potent dopamine antagonist and a selective muscarinic M4 receptor agonist with an EC50 of 11 nM.

  • Major metabolite of Clozapine
  • Activates human muscarinic designer receptors (DREADDs) hM3Dq and hM4Di
  • Cannot cross the blood-brain barrier
  • Clozapine is a potent dopamine antagonist and selective muscarinic M4 receptor agonist
  • Appearance: Solid
  • Color: Light yellow to yellow

Catalog No. 50-003-84623


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