AdipoGen Clusterin mouse pAb

Supplier:  AdipoGen AG25A0054C100

Polyclonal Antibody. Recognizes mouse clusterin. Detects a band of ~48kDa by Western blot. Source Rabbit. Applications ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits produced by internal cleavage. Clusterin is expressed in virtually all tissues and found in all fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

Catalog No. 50-256-3258