AdipoGen Clusterin SF hrec

Supplier:  AdipoGen AG40A0050YC010

Protein. Signal peptide sequence and the human secretory clusterin aa 1-449 are fused at the C-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >90% SDS-PAGE. Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80kDa disulfide-linked heterodimer of alpha and beta subunits produced by internal cleavage. Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling and immune system regulation. Clusterin also exists as a nuclear protein.

Catalog No. 50-256-3038