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Medchemexpress LLC Cmpd-39 | 2242582-40-5 | 99.7% | C26H28FN3O4S | 1 MG
SDP

Catalog No. 5000353447
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CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 with an IC50 of approximately 20 nM. It demonstrates high selectivity over other DUB family members. This compound promotes phosphoubiquitin accumulation, accelerating mitochondrial and peroxisomal autophagy, and has shown to restore impaired mitochondrial function in Parkinson's disease patient neurons.

  • Selective non-covalent inhibitor of USP30
  • Demonstrates high selectivity over other DUB family members
  • Enhances ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP
  • Promotes mitochondrial autophagy (mitophagy)
  • Promotes peroxisomal autophagy (pexophagy)
  • Restores impaired mitochondrial function in Parkinson's disease models

Catalog No. 50-003-53447 Supplier Medchemexpress LLC Supplier No. HY1416591MG
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CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 with an IC50 of approximately 20 nM. It demonstrates high selectivity over other DUB family members. This compound promotes phosphoubiquitin accumulation, accelerating mitochondrial and peroxisomal autophagy, and has shown to restore impaired mitochondrial function in Parkinson's disease patient neurons.

  • Selective non-covalent inhibitor of USP30
  • Demonstrates high selectivity over other DUB family members
  • Enhances ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP
  • Promotes mitochondrial autophagy (mitophagy)
  • Promotes peroxisomal autophagy (pexophagy)
  • Restores impaired mitochondrial function in Parkinson's disease models

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