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Medchemexpress LLC CNQX | 115066-14-3 | MFCD00069232 | C9H4N4O4 | 100 MG
Supplier: Medchemexpress LLC HY15066100MG
CNQX (FG9065) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. It functions as a competitive non-NMDA receptor antagonist and has been shown to block the expression of fear-potentiated startle in rats.
- Potent and competitive AMPA/kainate receptor antagonist
- IC50s of 0.3 μM for AMPA and 1.5 μM for kainate
- Functions as a competitive non-NMDA receptor antagonist
- Blocks expression of fear-potentiated startle in rats
- Reversibly blocks Schaffer collateral and mossy fibre EPSP in hippocampal slices
- Selectively reduces amplitude of monosynaptic component of DR-VRR in lumbar spinal segments
- Decreases cocaine responses in a dose-dependent manner in rats
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