Coenzyme Q-10, 98+%

Description

Component of electron transport chain and in aerobic cellular respiration | CAS: 303-98-0 | C59H90O4 | 863.37 g/mol

It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Solubility
Soluble in chloroform.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 303-98-0
• Molecular Formula: C59H90O4
• Molecular Weight (g/mol): 863.37
• MDL Number: MFCD00042919
• InChI Key: ACTIUHUUMQJHFO-UPTCCGCDSA-N
• Synonym: coenzyme q10, ubidecarenone, ubiquinone 50, coq10, ubiquinone-10, neuquinon, ubiquinone, justquinon, neuquinone, emitolon
• PubChem CID: 5281915
• ChEBI: CHEBI:46245
• SMILES: COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O

• Melting Point: 48°C to 52°C
• Color: Yellow to Orange
• Quantity: 1 g
• Beilstein: 1900141
• Sensitivity: Light sensitive
• Merck Index: 14,9843
• Solubility Information: Soluble in chloroform.
• IUPAC Name: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
• Formula Weight: 863.36
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Coenzyme Q-10

Safety and Handling

EINECSNumber	206-147-9
RTECSNumber	DK3900000
TSCA	Yes
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only