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Apexbio Technology LLC Colchicine 64-86-8 500mg
Supplier: Apexbio Technology LLC A3324500
Colchicine (CAS 64-86-8) is a small-molecule inhibitor targeting tubulin polymerization It binds directly to tubulin monomers disrupting their polymerization into microtubules (IC50 3 2 M) By preventing microtubule assembly colchicine interferes with spindle formation arresting cells in mitosis at metaphase thereby functioning as a mitotic inhibitor Additionally colchicine demonstrates anti-inflammatory activity by suppressing neutrophil motility and function reducing urate crystal deposition and has been effectively used in animal models of gouty arthritis It is widely utilized in biomedical research to study microtubule dynamics mitosis control and inflammatory pathways
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