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Medchemexpress LLC Colchicine | 64-86-8 | 99.9% | 399.44 | 100 MG
Supplier: Medchemexpress LLC HY16569100MG
Colchicine is an orally active alkaloid that acts as a potent tubulin inhibitor and a microtubule disrupting agent. It is intended for research and analytical applications.
- Inhibits microtubule polymerization with an IC50 of 3 nM.
- Acts as a competitive antagonist of the α3 glycine receptors (GlyRs).
- Prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome.
- Possesses extensive anti-inflammatory, immunosuppressive, and strong anti-fibrosis effects.
- Has potential for gouty arthritis research.
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Can be used to induce Alzheimer's disease models.
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