Colchicine (Standard) is the analytical standard for Colchicine, an orally active alkaloid. It acts as a potent tubulin inhibitor and a microtubule disrupting agent, inhibiting microtubule polymerization with an IC50 of 3 nM. It also functions as a competitive antagonist of α3 glycine receptors (GlyRs) and can prevent NSAID-induced small intestinal injury. Colchicine demonstrates extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects, suggesting its potential for gouty arthritis research.
- Analytical standard for research and analytical applications.
- Potent tubulin inhibitor and microtubule disrupting agent.
- Inhibits microtubule polymerization with an IC50 of 3 nM.
- Competitive antagonist of the α3 glycine receptors (GlyRs).
- Prevents NSAID-induced small intestinal injury.
- Extensive anti-inflammatory, immunosuppressive, and anti-fibrosis effects.
- Potential for gouty arthritis research.