Colchicine, 95% (dry wt.), Thermo Scientific Chemicals

Description

Colchicine is used as an anti-inflammatory agent for long-term treatment of behcet's Disease. It is used for constipation-predominant irritable bowel syndrome in women, and for treatment of severe or persistent aphthous stomatitis (canker sores).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water and alcohol. Sparingly soluble in ether.

Notes
Incompatible with strong oxidizing agents and mineral acids.

Specifications

Chemical Identifiers

• CAS: 64-86-8
• Molecular Formula: C22H25NO6
• Molecular Weight (g/mol): 399.44
• MDL Number: MFCD00078484,MFCD00078484
• InChI Key: IAKHMKGGTNLKSZ-INIZCTEOSA-N
• Synonym: colchicine, colchicina, colchicin, condylon, colchicinum, colchisol, colsaloid, colcin, colchineos, 7alphah-colchicine
• PubChem CID: 45038708
• SMILES: COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1

• Melting Point: ∼150°C (decomposition)
• Quantity: 1 g
• UN Number: UN1544
• Beilstein: 2228813
• Sensitivity: Light sensitive
• Merck Index: 14,2471
• Solubility Information: Soluble in water and alcohol. Sparingly soluble in ether.
• IUPAC Name: 2,2,2-trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
• Formula Weight: 399.44
• Percent Purity: 95%
• Assay: (dry wt.)
• Chemical Name or Material: Colchicine

Safety and Handling

Hazard Category	H300-H340
Hazard Statement	GHS H Statement H300-H340 Fatal if swallowed. May cause genetic defects.
Precautionary Statement	P201-P202-P264b-P270-P281-P301+P310-P308+P313-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: ALKALOIDS, SOLID, N.O.S.
EINECSNumber	200-598-5
RTECSNumber	GH0700000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only