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Apexbio Technology LLC Colistin Methanesulfonate (sodium salt)(Synonyms: Colistimethate sodium, Colistin sodium methanesulfonate, CMS, Sodium colistimethate), 5g, CAS: 8068-28-8.

Supplier: Apexbio Technology LLC C30465000
Colistin methanesulfonate (sodium salt CAS 8068-28-8) is an inactive prodrug of colistin (polymyxin E) a polypeptide antibiotic derived from Paenibacillus polymyxa strains It targets Gram-negative bacteria by disrupting the integrity of bacterial outer membranes leading to bacterial cell death In vitro analyses indicate concentration-dependent bactericidal activity against Pseudomonas aeruginosa requiring significantly elevated levels above minimum inhibitory concentrations (MIC) for complete microbial eradication It serves primarily as a tool compound for exploring antimicrobial mechanisms and resistance dynamics in Gram-negative pathogens
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