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  6. Colistin sodium methanesulfonate

Colistin sodium methanesulfonate

Catalog No. AAJ6669803
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Catalog No. AAJ6669803 Supplier Thermo Scientific Chemicals Supplier No. J6669803
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Description

CAS: 8068-28-8 | C58H105N16Na5O28S5 | 1749.811 g/mol

Colistin sodium methanesulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination. It is used to study effective treatments of P. aeruginosa infections in cystic fibrosis patients and to study the pharmacokinetics and BAL concentration of colistin in critically ill patients

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Freely soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 8068-28-8
Molecular Formula C58H105N16Na5O28S5
Molecular Weight (g/mol) 1749.811
MDL Number MFCD00130824
InChI Key IQWHCHZFYPIVRV-KLWRPAJRSA-I
Synonym Colimycin sodium methanesulfonate; Polymyxin E sodium methanesulfonate
PubChem CID 131668505
IUPAC Name pentasodium;(6S)-N-[(2R)-1-[[(2R,3S)-3-hydroxy-1-[[(2S)-1-[[(3S,6S,9S,12S,15R,18S,21S)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-8,17,20-trioxido-2,5,11,14-tetraoxo-6,9,18-tris[2-(sulfomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricosa-7,16,
SMILES CCC(C)CCCCC(=NC(CCNCS(=O)(=O)O)C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)O)C(=NC1CCNC(=O)C(NC(=O)C(N=C(C(NC(=O)C(NC(=O)C(N=C(C(N=C1[O-])CCNCS(=O)(=O)O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)O)[O-])CCNCS(=O)(=O)O)C(C)O)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+]

Specifications

Type Colistin Sodium Methanesulfonate
Physical Form Powder
Color White to Yellow
Quantity 1 g
Merck Index 14,2479
Solubility Information Freely soluble in water
Formula Weight 1759.89
Chemical Name or Material Colistin sodium methanesulfonate

Safety and Handling

EINECSNumber 232-516-9
RTECSNumber GH1650000
TSCA Yes
storageNote1 2° to 8°C
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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