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Colistin sulfate

Catalog No. AAJ6091503
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Catalog No. AAJ6091503 Supplier Thermo Scientific Chemicals Supplier No. J6091503
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Description

Colistin Sulfate salt (2:5), CAS # 1264-72-8, (synonym: Polymyxin E Complex), is a complex mixture of antibiotics, with Colistin A and B being the primary components. It has anti-bacterial activity against Gram-positive and Gram-negative bacteria and may also be used as a neuromuscular blocker. | CAS: 1264-72-8

Colistin sulfate A Polymyxin potent antibiotic and apoptosis inducer. This compound induces apoptosis through interaction with the cytoplasmic membrane. Colistin is a key microbiological component in Colistin Oxolinic Acid Blood Agar utilized in the cultivation of Aminobacter aminovorans, Bacillus species, Hyphomicrobium species and Methylobacterium species. It is also a critical component is VCN Inhibitor & VCNT Inhibitor growth media used in the isolation of Neisseria species.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Colistin Sulfate salt is a stable, cationic, water-soluble, white powder composed of over 30 components
  • Originally isolated from B. polymyxa, it inhibits the growth of the Gram-negative (e.g. E. coli, P. aeruginosa, P. fluorescens, and S. enterica), and Gram-positive bacteria (e.g. L. lactis, P. polymyxa, P. acidilactici, and S. aureus) by permeabilizing the bacterial cell membrane

Applications

  • Colistin Sulfate has potent anti-endotoxin activity rendered through its ability to bind lippopolysaccharides that make up bacterial endotoxins
  • This compound is often used in the management of multi-drug resistant Gram-negative infections
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1264-72-8
MDL Number MFCD00146495
Synonym Polymyxin E

Specifications

Type Colistin Sulfate
Physical Form Powder
Color White
Quantity 1 g
UN Number UN2811
Merck Index 14,2479
Solubility Information Soluble in water
Chemical Name or Material Colistin sulfate

Safety and Handling

Hazard Category H301
Hazard Statement GHS H Statement
H301
Toxic if swallowed.
Precautionary Statement P264b-P270-P301+P310-P330-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 215-034-3
RTECSNumber TR1500000
TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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