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3HELIX R-CHP (Collagen Hybridizing Peptide, Cy3 Conjugate, 300ug) (RED300)
Supplier: 3HELIX RED300
The Collagen Hybridizing Peptide (CHP) is a novel probe that specifically targets damaged collagen in vitro and in vivo. By mimicking the Gly-X-Y repeating sequence, it hybridizes with denatured collagen chains to reform the triple helix. This mechanism provides exceptional specificity with minimal non-specific binding. As a powerful histopathology tool, CHP enables straightforward detection of collagen degradation across a wide range of applications. It can be used to visualize tissue damage from inflammation, disease, or aging; track pericellular matrix turnover during cancer cell migration; measure molecular-level mechanical injury; assess collagen in decellularized matrices; and detect collagen bands on SDS-PAGE gels without Western blotting. R-CHP is labeled with sulfo-Cyanine3 for direct fluorescence detection.
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