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AdipoGen Collagen Type 1 3 4 frag pAb
Supplier: AdipoGen AG25T0116C025
Polyclonal Antibody. Recognizes rat and bovine collagen type 1. Based on sequence identity should also recognize human, mouse, guinea pig, dog, cat, donkey, pig, cow, sheep and chicken collagen type 1. Source Rabbit. Applications ICC. Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide. The proteolysis of collagens plays an important role in numerous physiological and pathological situations such as morphogenesis, wound healing, arthritis, arteriosclerosis and tumor metastasis. Triple helical type I collagens are made up of two alpha1 I and one alpha2 I chains, and are found in skin, tendon, ligament and interstitial tissues. Due to their fibrillary structure native collagens are resistant to most proteases. They are substrates for certain matrix metalloproteinases MMPs, which constitute a family of zinc-dependent enzymes catalyzing the degradation of extracellular matrix components.
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