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ABclonal Technology COMP Rabbit mAb
Supplier: ABclonal Technology A22260100UL
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein It consists of five identical glycoprotein subunits each with EGF-like and calcium-binding (thrombospondin-like) domains Oligomerization results from formation of a five-stranded coiled coil and disulfides Binding to other ECM proteins such as collagen appears to depend on divalent cations Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)
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