Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Complement C3 Protein, Cynomolgus (HEK293, His) | 90.6% | Approximately 70, 115, 190 kDa | 50 UG
Supplier: Medchemexpress LLC HYP7533250UG
Complement C3 proteins play a pivotal role in initiating the complement system, with processing by C3 convertase central to both classical and alternative pathways. Upon activation, C3b can covalently bind to cell surface carbohydrates or immune aggregates via its reactive thioester. The anaphylatoxin C3a, a result of proteolytic degradation, mediates local inflammatory processes. This product is a recombinant cynomolgus-derived Complement C3 protein, expressed by HEK293 cells, with a C-His labeled tag. In chronic inflammation, C3a acts as a chemoattractant for neutrophils, inducing smooth muscle contraction, increasing vascular permeability, and triggering histamine release.
- Species: Cynomolgus
- Source: HEK293
- Tag: C-His
- Enhances IL-6 secretion by THP-1 human acute monocytic leukemia cells
- Formulated as a lyophilized powder from a 0.22 μm filtered solution of PBS, pH 7.4
- Endotoxin level: <1 EU/μg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?