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ABclonal Technology Complement factor D Rabbit mAb
Supplier: ABclonal Technology A2300620UL
This gene encodes a member of the S1 or chymotrypsin family of serine peptidases This protease catalyzes the cleavage of factor B the rate-limiting step of the alternative pathway of complement activation This protein also functions as an adipokine a cell signaling protein secreted by adipocytes which regulates insulin secretion in mice Mutations in this gene underlie complement factor D deficiency which is associated with recurrent bacterial meningitis infections in human patients Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease
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