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Selleck Chemical LLC Compound E S0058-5MG
SDP

Catalog No. 5000039764
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Compound E ( -Secretase-IN-1) is a potent inhibitor of -secretase which blocks -secretase-mediated cleavage of Notch with an IC50 of 0 32 nM It also suppresses the production of -amyloid(40) and -amyloid(42) with IC50 values of 0 24 nM and 0 37 nM respectively It also inhibits Notch signalling significantly disrupting gonadotropin-dependent follicle growth and halting progression to the preovulatory stage of development

Catalog No. 50-000-39764 Supplier Selleck Chemical LLC Supplier No. S00585MG
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Compound E ( -Secretase-IN-1) is a potent inhibitor of -secretase which blocks -secretase-mediated cleavage of Notch with an IC50 of 0 32 nM It also suppresses the production of -amyloid(40) and -amyloid(42) with IC50 values of 0 24 nM and 0 37 nM respectively It also inhibits Notch signalling significantly disrupting gonadotropin-dependent follicle growth and halting progression to the preovulatory stage of development

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