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Enzo Life Sciences Compound E, (250µg), CAS Number: 209986-17-4
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Supplier:  Enzo Life Sciences ALX270415C250

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γ-Secretase inhibitor. Cell permeable, potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50=0.3nM for total β-amyloid) and Notch processing, which ceases cell differentiation. At higher concentrations (20-400µM), only weakly affects the presenilase activity. Activity tested!. Alternative Name: (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide, γ-Secretase Inhibitor, GSI. Formula: C27H24F2N4O3. MW: 490.5. CAS Number: 209986-17-4. Purity: ≥95% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: -20°C

Catalog No. 50-103-1739


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