Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Concanavalin A, MP Biomedicals™
Click to view available options
Quantity:
250 mg
500 mg
Description
Lectin are used in a wide variety of applications. Con-A is not a glycoprotein and does not contain cysteine residues. Unlike most other lectins, Con-A is a metalloprotein and requires a transition metal ion, such as manganese, plus calcium ions for binding.
- Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Con-A binds specifically to mannosyl and glucosyl residues of polysaccharides and glycoproteins.
- Unmodified hydroxyl groups at the C3, C4 and C6 positions of D-glucopyranosyl or D-mannopyranosyl rings may be essential for binding.
- Each subunit of Con A contains one calcium ion and one manganese ion. Removal of these cations by dialysis under acidic conditions abolishes the carbohydrate-binding activity.
- Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer. Above pH 7.0 higher aggregates are formed.
- Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Specifications
Specifications
Quantity | 500 mg |
Solubility Information | Soluble in water (10mg/mL, slightly hazy, colorless solution). |
Formula Weight | Monomeric molecular weight of Con-A is 25,500(Lit.) |
Physical Form | Powder |
Safety and Handling
Recommended Storage | −20°C |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction