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Apexbio Technology LLC Conduritol B epoxide 6090-95-5 25mg
Supplier: Apexbio Technology LLC C444825
Conduritol B epoxide (CAS 6090-95-5) is a well-characterized inhibitor of -glucosidase an enzyme responsible for cleaving glycosidic bonds in -D-glucosides and oligosaccharides releasing glucose It exhibits an in vitro IC50 of 9 M and acts as an active-site-directed irreversible inhibitor for several glucosidases its inactivation effect can be abrogated in the presence of alternative substrates such as maltose In vivo studies following intraperitoneal administration in mice reveal rapid tissue distribution excluding the brain and pronounced accumulation in the kidney with a tissue excretion half-life of approximately 7 hours Conduritol B epoxide rapidly inhibits tissue -glucosidase activity supporting its utility as a tool compound in glycosidase function and lysosomal storage disorder research
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