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Medchemexpress LLC COR659 | 544450-68-2 | 99.9% | 337.82 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13720450MG

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COR659 is a potent and effective GABAB positive allosteric modulator (PAM). It suppresses alcohol and chocolate self-administration in rats. It appears to act through a composite mechanism, including positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor.

  • Potent and effective GABAB positive allosteric modulator (PAM).
  • Suppresses alcohol and chocolate self-administration in rats.
  • Effective in reducing lever-responses for sucrose and chocolate solutions in rats.
  • In vivo studies indicate no effect on lever-responding for regular food pellets in food-deprived Wistar rats.
  • Demonstrates a dose-dependent reduction in lever-responses for alcohol in rats.

Catalog No. 50-003-51551


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