Corning™ BioCoat™ Collagen IV Multiwell Plates

Description

Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells.

• Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation.

Applications include:

• Promotion of cell attachment and spreading
• Cell differentiation and neurite outgrowth
• Increased proliferation of PC12 cells
• Studies of effects of collagen IV on cell behavior
• Cell adhesion assays

Source

• Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor

Quality Control

• Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
• Tested and found negative for bacteria and fungi
• Collagen IV purity >90% by SDS-PAGE

Storage

• 2°C to 8°C. Do not freeze.

Specifications

• Array: 2 x 3
• Closure Color: Clear
• Closure Included: Yes
• Closure Material: Polystyrene
• Bottom Shape: Flat
• Color: Clear
• Material: Polystyrene
• Shape: Rectangular
• Sterility: Non-sterile
• Surface Treatment: ECM/Attachment Factors
• Type: Multi-well Cell Culture Plate
• Well Count: 6
• For Use With (Application): Promotion of cell attachment and spreading, rapid expansion of cell populations, serum-free or reduced serum culture, cell adhesion assay, improving survival of primary cells in culture
• Includes: Lid
• No. per Case: 5/Cs.
• No. per Pack: 1/Pk.
• Quantity: 5/Cs.
• Source: EHS Lathrytic Mouse Tumor
• Storage Requirements: 2°C to 8°C

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov