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Cayman Chemical Cornus ofcnals Cornusde 10mg

Supplier: Cayman Chemical 3628410 MG
A bisiridoid glycoside with diverse biological activities; induces osteogenic differentiation of isolated human BMSCs at 10, 30, and 60 µM; reduces demyelination, focal inflammation, and Th17 cell spinal cord infiltration, as well as improves neurological deficits in a rat model of EAE at 150 mg/kg; decreases mortality, vascular instability, and pulmonary leukocyte infiltration in a mouse model of cecal ligation and puncture-induced sepsis at 0.4 and 0.8 mg/kg; reduces polydipsia and polyphagia, lowers fasting blood glucose levels, prevents testicular cell apoptosis, and decreases the abundance of Weissella, Clostridium, Anaerotruncus, and Bilophila in the gut microbiome in KK/Ay diabetic mice
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