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TARGETMOL CHEMICALS INC CORNUSIDE 5MG
Supplier: TARGETMOL CHEMICALS INC T4S23265MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardial I/R and protect the liver from CCl4-induced acute hepatotoxicity by reducing oxidative stress and suppressing inflammatory responses. 4. Cornuside has anti-inflammatory activity by downregulations of iNOS and COX-2 due to NF-(kappa)B inhibition as well as the negative regulation of ERK1/2 p38 and JNK1/2 phosphorylations in RAW 264.7 cells. 5. Cornuside has protective potential against cerebral ischemic injury may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity and improvements in mitochondrial energy metabolism and antioxidant properties. purity: 99%
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