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Cayman Chemical Cortex fraxInI FraxetIn 50mg
Supplier: Cayman Chemical 2801150 MG
A coumarin with diverse biological activities; scavenges DPPH radicals, ABTS radicals, and hydrogen peroxide in cell-free assays (IC50s = 44.1, 37.4, and 40.5 μM, respectively); selectively reduces cell viability in a panel of six NSCLC cell lines (IC50s = 20.12-61.36 μM) over noncancerous cell lines (IC50s = >100 μM); reduces levels of AST, ALT, and TBIL in serum, decreases hepatic expression of TNF-α, IL-6, IL-1β, and COX-2, and attenuates hepatic fibrosis in a rat model of carbon tetrachloride-induced liver fibrosis at 25 and 50 mg/kg
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