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Cayman Chemical Corynoxen 10mg
Supplier: Cayman Chemical 3140310 MG
An alkaloid with diverse biological activities; inhibits LPS-induced production of NO in primary rat microglia (IC50 = 15.7 µM); inhibits PDGF-BB-induced ERK1/2 activation in, and proliferation of, rat aortic VSMCs from 5-50 µM; inhibits compound 48/80-induced histamine release from LAD 2 mast cells from 25-200 µM; reduces compound 48/80-induced local anaphylaxis and mast cell degranulation in mouse hind paws at 0.5, 2.5, and 5 mg/kg; reduces methamphetamine-induced hyperlocomotion in mice at 30 and 100 mg/kg
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