Cayman Chemical Coydals ynusuo Coydaln 100mg

Supplier:  Cayman Chemical 27654100 MG

An inhibitor of Src and p38 MAPK kinases (Kds 2 7 2 2 and 5 5 nM for c-Src p38a and p38B respectively) also inhibits Fyn Yes Lyn Abl Arg Ack Csk EphB2 EphB4 and Zak at 500 nM inhibits cell growth in a panel of TNBC cell lines (IC50s 6 1-260 nM) and in a patient-derived TNBC cell line (IC50 320 nM) induces cell cycle arrest at the G1/S phase MDA-MB-231 and SUM149 cells at 1 M inhibits cell motility and invasion in MDA-MB-231 and SUM149 cells at 50 nM reduces tumor growth in SUM149 and MDA-MB-231 mouse xenograft models at 10 mg/kg

Catalog No. 50-294-0706