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Cayman Chemical CP 100 356hydrochlorIde 10mg
Supplier: Cayman Chemical 3285310 MG
A P-glycoprotein inhibitor (IC50 = 0.5 µM); selective for P-gp over MRP2 at 15 µM, CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 (IC50s = >50 µM for all), and OATP2B1 (IC50 = ~66 µM) but does inhibit BCRP (IC50 = 1.5 µM); increases the rate of prazosin clearance in rats at 24 mg/kg when administered in combination with prazosin
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