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Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG
Supplier: Medchemexpress LLC HY15259A100MG
CP-640186 hydrochloride is an orally active and cell-permeable inhibitor of Acetyl-CoA carboxylase (ACC). It exhibits IC50 values of 53 nM for rat liver ACC1 and 61 nM for rat skeletal muscle ACC2. ACC is a crucial enzyme involved in fatty acid metabolism, responsible for synthesizing malonyl-CoA. This compound also promotes muscle fatty acid oxidation.
- Orally active and cell-permeable.
- Inhibits Acetyl-CoA carboxylase (ACC).
- IC50s: 53 nM for rat liver ACC1, 61 nM for rat skeletal muscle ACC2.
- Stimulates muscle fatty acid oxidation.
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