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Cayman Chemical CP 809 101hydrochlorIde 10mg
SDP

Supplier:  Cayman Chemical 3328310 MG

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A potent 5-HT2C receptor agonist; selective for human 5-HT2C and rat 5-HT2C over human 5-HT2A, 5-HT2B, and rat 5-HT2A receptors in a FLIPR assay (EC50s = 0.11, 0.06, 153, 65.3, and 119 nM, respectively), as well as human dopamine D2, histamine H1, and α1- and α2-adrenergic receptors (Kis = 872, 828, 217, and 956 nM, respectively); inhibits the conditioned avoidance response, hyperactivity induced by PCP and D-amphetamine, and spontaneous locomotor activity in rats (ED50s = 4.8, 2.4, 2.9, and 2 mg/kg, respectively); reduces reinstatement of drug-seeking behavior in cocaine-primed rats (0.01-1 μg/0.2 μl/side in the central amygdala)

Catalog No. 50-294-6351


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