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Genscript Corporation cPass SARS-CoV-2 Neutralizati
Supplier: Genscript Corporation L00847
The b GenScript SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT) Kit /b can detect circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain of the viral spike glycoprotein (RBD) with the ACE2 cell surface receptor The assay detects any antibodies in serum and plasma that neutralize the RBD-ACE2 interaction The test is both species and isotype independent br/ br/ The b SARS-CoV-2 sVNT Kit /b is a blocking ELISA detection tool which mimics the virus neutralization process The kit contains two key components the Horseradish peroxidase (HRP) conjugated recombinant SARS-CoV-2 RBD fragment (HRP-RBD) and the human ACE2 receptor protein (hACE2) The protein-protein interaction between HRP-RBD and hACE2 can be blocked by neutralizing antibodies against SARS-CoV-2 RBD br/ First the samples and controls are pre-incubated with the HRP-RBD to allow the binding of the circulating neutralization antibodies to HRP-R
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